Prolia can also increase this risk. Prolia is also available in a biosimilar form. You may take the carton out of the refrigerator and allow it to reach room temperature before the injection is given. Below, we answer some common questions about taking Prolia. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Prolia can cause certain side effects, some of which are more common than others. But they each work differently because Prolia is a monoclonal antibody (it may also be called a miscellaneous bone resorption agent) and Reclast is a bisphosphonate which means they have different side effects, other uses, tolerability, and effectiveness profiles. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Learn more details about some of the side effects that Prolia may cause. Some people may have an allergic reaction to Prolia. Your doctor can also advise you on symptoms of low calcium to look for. If youve been diagnosed with osteoporosis, your doctor may discuss Prolia with you. Prolia (Injection) Uses, Dosage & Side Effects - Drugs.com Breastfeeding. Drug class: miscellaneous bone resorption inhibitors. Musculoskeletal pain from Prolia is mild or manageable for most people. This includes proper brushing, flossing, mouthwash use, and regular professional dental cleanings. But its not clear how often this side effect occurred in clinical trials. Prolia is sometimes used in people whose bone fracture is caused by certain medicines or cancer treatments. you can take. Yoga for Osteoporosis: 5 Beneficial Poses, Diet and Osteoporosis: Nutrients, Diet Tips, and More. Are there lifestyle changes that can help my osteoporosis. It is not known if the use of Prolia over a long period of time may cause slow healing of broken bones. It is not safe to receive Prolia during pregnancy. They can also tell you about other treatment options available for osteoporosis and bone loss prevention. Muscle pain often contributes to back pain, one of the most common side effects reported in clinical trials of Prolia. If you develop hypocalcemia, your doctor will typically have you stop using Prolia. Special care may be needed. These are not all the possible side effects of Prolia. You should also take calcium and vitamin D supplements while being Take calcium and vitamin D as your doctor tells you to help prevent low blood calcium. Do not use denosumab if you are pregnant. Calcium supplements may help support bone and teeth health. The use of the eHealthMe site and its content is at your own risk. This is called hypocalcemia. kidney disease (or if you are on dialysis); a weak immune system (caused by disease or by using certain medicines); hypoparathyroidism (decreased functioning of the parathyroid glands); any condition that makes it hard for your body to absorb nutrients from food (malabsorption); if you are scheduled for a dental procedure; if you cannot take daily calcium and vitamin D; or. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. Different individuals may respond to medication in different ways. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. If you develop high cholesterol with Prolia, your doctor can guide you on which treatment options are right for your condition. Copyright 1996-2023 Cerner Multum, Inc. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Prolia can cause many serious side effects. Taking medications, vaccines, foods, and other things with a certain drug can affect how the drug works. or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. If you keep this medicine at home, store it in the original carton in a refrigerator. This means your bones may be weaker than usual. eHealthMe is studying from 138,307 Prolia users for its effectiveness, alternative drugs and more. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. Prolia may not be right for you if you have certain medical conditions or other factors that affect your health. But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types). In addition, your doctor will most likely recommend that you take calcium and vitamin D supplements while taking bisphosphonates, since vitamin D helps your body to absorb calcium. WebDrug interactions are reported among people who take Prolia and Calcium. So your healthcare provider will likely ask you to take calcium and vitamin D supplements if youre not taking them already. But if they become bothersome, talk with your doctor or pharmacist. Prolia is used in adults to treat osteoporosis or bone loss in people who: who cannot use another osteoporosis medicine or these medicines did not work well. Prolia injection is a brand of denosumab, which treats osteoporosis. What are the possible side effects of Prolia? Prolia has active ingredients of denosumab. And some of these side effects are more common with certain uses of Prolia. With bone loss, your body loses old bone tissue faster than it makes new bone tissue. More than half of American adults take an herbal or dietary supplement, and many more use over-the-counter or prescription drugs to manage maladies ranging from the occasional headache to chronic health conditions or mood disorders.. For many, it is part of their daily routine. Your risk may also be higher if you: Stopping Prolia treatment can also increase your risk for bone fractures. Based on your dental history, your doctor can discuss with you the risks of using Prolia. These factors include what your insurance plan covers. If you are pregnant, you should not take Prolia. Is the ketogenic diet right for autoimmune conditions? Learn more about some of the side effects Prolia may cause. Specifically, its used to increase bone mass in: Osteopenia (low bone mass), and low bone mineral density (BMD) can occur with older age. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. (2021). Prolia solution is available in one strength: 60 milligrams per milliliter (mg/mL). Prolia may cause serious side effects. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. Because Prolia can also cause low blood calcium, your risk may increase if you receive Prolia. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. WebIn many individuals, calcium supplements are better absorbed when taken with food. WebYour doctor may prescribe calcium and vitamin D to help prevent low calcium levels in Theyll also usually treat the hypocalcemia right away. But weight gain may occur with other medications you take or other health conditions you have. Healthline Media does not provide medical advice, diagnosis, or treatment. Stopping some drugs leads to withdrawal symptoms because your body is used to the drug and needs it for you to feel normal. Version: 13.01. hydrochlorothiazide, alendronate, Fosamax, calcium carbonate, Premarin, Tymlos. For example, an over-the-counter pain reliever can often ease mild pain such as joint or muscle pain, or headache. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Prolia You may report side effects to FDA at 1-800-FDA-1088. These side effects may be temporary, lasting a few days or weeks. However, drinking too much alcohol may raise your risk of falling. If you miss a dose of Prolia, you should receive your injection as soon as you can. It comes as a liquid solution thats given as an injection. may occur. You should use an effective method of birth control (contraception) during treatment with Prolia and for at least 5 months after your last dose of Prolia. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Follow your doctor's instructions about any restrictions on food, beverages, or activity. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.) such as inflammation of your skin (dermatitis), rash, and eczema have been reported. Prolia comes as a solution thats given as an injection under your skin. We comply with the HONcode standard for trustworthy health information. Like Helpful Hug REPLY 1 reply Mamie | @mamie | Oct They may give you tips on managing a body weight thats healthy for you. Also, its important to brush and floss your teeth regularly while youre using Prolia. Talk with your doctor about which other treatments are better choices for you. If youve had surgery on your thyroid or parathyroid glands, you may have an increased risk of a low level of calcium in your blood. If you are a healthcare professional, click "I Agree" to continue. Talk with your doctor about the best options for treating your condition. All rights reserved. (Biosimilars are like generic drugs. You may need to have a dental exam before you begin treatment with Prolia. What should be considered before taking Prolia? For example, if you have a serious UTI or other infection, call your doctor right away. Osteoporosis (Biosimilars are like generic drugs. Call your doctor for instructions if you miss a dose or miss an appointment for your Prolia injection. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. These can include tingling or numbness in the hands, feet, and face. Prolia can cause peripheral edema (fluid retention) or swelling, and this may lead to weight gain in some people. Prolia may cause several side effects. If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. Call your doctor for medical advice about side effects. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.). This aids in keeping your calcium level within the recommended range. Policy. The Prolia is making my leg bones and jaw bones hurt. What Health Changes Should You Expect Postmenopause? Continue reading. If your dizziness doesnt go away or becomes severe, talk with your doctor. Youll receive Prolia doses from a healthcare professional. Prolia can also cause bones to not form correctly and reduced growth in a fetus. What should I know about Prolia vs. Boniva? Below are answers to some commonly asked questions about Prolia. Denosumab is contraindicated in women with hypocalcaemia. You may have questions about Prolia and your treatment plan. They can help answer any questions you have about side effects from taking the drug. The lists below describe some of the more common side effects that Prolia may cause. It is important not to miss your dose. This list doesnt include all possible mild side effects of the drug. Be sure to talk with your doctor about which medication is right for you. And ask your doctor about which drug is right for your condition. 1 shot every 6 months could mean fewer doses. But doing so can cause more bone breakdown and increase your risk for bone fractures. Prolia is injected under the skin. So treatment with the drug requires you to take daily calcium and vitamin D supplements. Use of the terms female and male in this article refers to sex assigned at birth. Do any of yall know? Nonmetastatic means the cancer hasnt spread to other areas of the body. Its important to tell your doctor if you have serious or ongoing side effects. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. If youre concerned about unexplained weight gain while using Prolia, talk with your doctor. If the user is trying to grow bone due to osteoporosis, osteopenia, or any reason, the recommended intake is 4 capsules divided into 2 doses also taken in the morning and evening with food. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Please know that the sponsors of this site are not responsible for content on the site you are about to enter. The most common side effects of Prolia in men with osteoporosis are back pain, joint pain, and common cold (runny nose or sore throat). have happened in people who take Prolia. DENOSUMAB (den oh sue mab) slows bone breakdown. Compared to other osteoporosis treatments, only Proliais1 shot every 6 months. For more information on this side effect, see Side effect specifics below. Ask your doctor about your own risk. You should also talk with them if you have any serious side effects during Prolia treatment. Starting an osteoporosis drug? Here What should I know about Prolia vs. Zometa? You may need to have a negative pregnancy test before starting this treatment. All subjects in the clinical trials of Prolia received 800mg of calcium and We avoid using tertiary references. Courtney Sullivan, Certified Yoga Instructor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Do not take this medicine with any of the following medications: This medicine may also interact with the following medications: This list may not describe all possible interactions. Prolia Frequently Asked Questions (FAQs) WebProlia is used to treat osteoporosis in women after menopause and in men, and in people Others may continue for as long as you take the drug, but they can be easily managed. Bone density decreases with time, and some people have a risk of developing weak or brittle bones. Prolia WebTake calcium and vitamin D as directed by your doctor, usually 1000 milligrams of No, weight gain wasnt reported as a side effect of Prolia in clinical trials. Most side effects from Prolia are mild and can go away on their own within a few days or weeks. What should I know about Prolia vs. Fosamax? Get emergency medical help if you have signs of an allergic reaction to Prolia: hives, itching, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat. Its used to lower the risk of bone fractures in people with certain other conditions. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs. The most common side effects of Prolia in patients receiving certain treatments for prostate or breast cancer are joint pain, back pain, pain in your arms and legs, and muscle pain.
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